iGenomix ERA PET Calculator
This calculator provides estimates only. Always consult with your fertility specialist for personalized timing.
For couples undergoing in vitro fertilization (IVF), the iGenomix ERA PET (Endometrial Receptivity Analysis Personalized Embryo Transfer) test represents a groundbreaking advancement in reproductive medicine. This innovative diagnostic tool helps identify the optimal window for embryo implantation, potentially increasing the chances of successful pregnancy for women who have experienced repeated implantation failure.
What is the iGenomix ERA PET Test?
The ERA PET test is a molecular diagnostic tool that analyzes the endometrium (uterine lining) to determine its receptivity to embryo implantation. Unlike traditional methods that rely on ultrasound or hormone levels, the ERA PET test examines 248 different genes to precisely identify when the endometrium is most receptive.
This test is particularly valuable for:
- Women who have experienced multiple failed IVF cycles with good-quality embryos
- Patients with unexplained infertility
- Those with suspected endometrial factor infertility
- Women considering frozen embryo transfer
How the ERA PET Test Works: A Step-by-Step Process
The ERA PET test involves a carefully timed procedure:
- Cycle Preparation: Your fertility specialist will prepare your endometrial lining using hormones, similar to a standard frozen embryo transfer cycle.
- Endometrial Biopsy: A small sample of your endometrial tissue is collected in a quick office procedure (typically on what would be day 5 of progesterone exposure in a standard cycle).
- Genetic Analysis: iGenomix analyzes the gene expression profile of your endometrial sample to determine receptivity status.
- Personalized Results: The test identifies whether your endometrium was receptive or non-receptive at the time of biopsy, and if non-receptive, provides guidance for optimal timing.
Key Benefits of the ERA PET Test
The iGenomix ERA PET test offers several important advantages:
1. Personalized Embryo Transfer
Identifies your unique “window of implantation” rather than relying on population averages.
2. Improved Success Rates
Studies show pregnancy rates increase when transfers are timed according to ERA results.
3. Reduced Emotional Burden
Helps minimize the frustration of repeated failed cycles by addressing potential endometrial factors.
Who Should Consider the ERA PET Test?
While the ERA PET test isn’t necessary for all IVF patients, it may be particularly beneficial for:
- Women with 2+ failed IVF cycles with good-quality embryos
- Patients with thin endometrium or other endometrial concerns
- Those with irregular menstrual cycles
- Women over age 35 undergoing IVF
- Patients considering single embryo transfer to maximize success
Understanding Your ERA PET Timing
The timing of your ERA PET biopsy is crucial for accurate results. Our calculator above helps estimate the optimal day for your procedure based on your individual cycle characteristics. However, always follow your fertility specialist’s specific instructions, as they may adjust timing based on your medical history and response to medications.
ERA PET Test Success Rates and Clinical Evidence
Clinical studies have demonstrated promising results:
| Study | Patient Group | Improvement in Pregnancy Rates |
|---|---|---|
| Ruiz-Alonso et al. (2013) | Women with previous implantation failure | 25% increase |
| Simon et al. (2017) | General IVF population | 15-20% increase |
| Recent iGenomix data | Personalized transfer timing | Up to 73% pregnancy rate |
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Frequently Asked Questions About ERA PET Testing
Is the ERA PET test painful?
Most women describe the endometrial biopsy as uncomfortable but tolerable, similar to a Pap smear with mild cramping. Your doctor may recommend taking pain medication beforehand.
How long does it take to get results?
iGenomix typically returns ERA PET results within 2-3 weeks after receiving the biopsy sample.
Does ERA PET guarantee pregnancy?
While ERA PET significantly improves implantation rates, it doesn’t guarantee pregnancy as many other factors affect IVF success. It does eliminate one major variable – transfer timing.
How much does the ERA PET test cost?
The test typically costs between $800-$1,200, plus biopsy procedure fees. Some insurance plans may cover part of the cost after multiple failed cycles.
Is the ERA PET Test Right for You?
The iGenomix ERA PET test represents a significant advancement in personalized reproductive medicine. By identifying your unique window of implantation, this test can help optimize your embryo transfer timing and potentially improve your chances of IVF success.
If you’ve experienced implantation failure or want to maximize your chances with each embryo transfer, discuss the ERA PET test with your fertility specialist. Together with other diagnostic tools and tailored treatment approaches, it may help you achieve your dream of parenthood.